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class=\"group-empty\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section>\n<section>\u8fc7\u53bb\u5341\u5e74\uff0c\u59dc\u9ec4\u7d20\u65e0\u7591\u662f\u81b3\u98df\u8865\u5145\u5242\u9886\u57df\u5f53\u4e4b\u65e0\u6127\u7684\u201c\u6297\u708e\u660e\u661f\u201d\u3002\u4ece\u6291\u5236NF-\u03baB\u5230\u4e0b\u8c03TNF-\u03b1\u548cCOX-2\uff0c\u5176\u591a\u9776\u70b9\u7cfb\u7edf\u8c03\u8282\u7684\u7279\u6027\u8ba9\u5b83\u51e0\u4e4e\u6210\u4e3a\u6162\u6027\u708e\u75c7\u7ba1\u7406\u7684\u6807\u914d\u3002\u7136\u800c\uff0c\u4e00\u4e2a\u53cd\u590d\u51fa\u73b0\u7684\u4e34\u5e8a\u53cd\u9988\u59cb\u7ec8\u672a\u80fd\u5f97\u5230\u5f88\u597d\u7684\u89e3\u7b54\uff1a\u201c\u575a\u6301\u5403\u4e86\u4e24\u4e09\u4e2a\u6708\uff0c\u5173\u8282\u75bc\u75db\u786e\u5b9e\u51cf\u8f7b\u4e86\uff0c\u4f46\u5982\u679c\u80fd\u518d\u5feb\u4e00\u70b9\u8be5\u591a\u597d\uff1f\u201d<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section>\n<section><\/section>\n<section>2025\u5e74\uff0c\u4e00\u9879\u9488\u5bf9\u8fd0\u52a8\u8bf1\u53d1\u6025\u6027\u808c\u8089\u9aa8\u9abc\u75bc\u75db\u7684\u968f\u673a\u53cc\u76f2\u5bf9\u7167\u8bd5\u9a8c\uff0c\u7ed9\u51fa\u4e86\u4e00\u4e2a\u60ca\u4eba\u7684\u6570\u5b57\uff1a<strong>\u5355\u6b21\u670d\u7528\u4e00\u79cd\u7279\u5b9a\u7684\u59dc\u9ec4\u4e0e\u4e73\u9999\u63d0\u53d6\u7269\u914d\u65b9\u540e\uff0c\u53d7\u8bd5\u8005\u57286\u5c0f\u65f6\u5185\u75bc\u75db\u51cf\u8f7b\u4e8698%<\/strong>\uff0c\u800c\u5b89\u6170\u5242\u7ec4\u51e0\u4e4e\u65e0\u53d8\u5316[1]\u3002\u540c\u6837\u4ee4\u4eba\u5370\u8c61\u6df1\u523b\u7684\uff0c\u662f\u75bc\u75db\u7684\u201c\u60c5\u611f\u8d1f\u62c5\u201d\u51e0\u4e4e\u88ab\u540c\u6b65\u5378\u9664\u2014\u2014<strong>\u201c\u75b2\u52b3-\u8017\u5c3d\u611f\u201d\u4ece61%\u9aa4\u964d\u81f33%<\/strong><strong>\uff0c\u201c\u538b\u75db\u201d\u4ece65%\u964d\u81f31%<\/strong>\u3002\u8fd9\u4e9b\u6570\u636e\u6307\u5411\u4e00\u4e2a\u6211\u4eec\u5c1a\u672a\u5145\u5206\u8ba4\u77e5\u7684\u9547\u75db\u7ef4\u5ea6\uff1a\u4e73\u9999\u63d0\u53d6\u7269\u4e0d\u4ec5\u80fd\u6251\u706d\u75bc\u75db\uff0c\u8fd8\u53ef\u80fd\u540c\u65f6\u5728\u6539\u5199\u5927\u8111\u5bf9\u75bc\u75db\u7684\u60c5\u7eea\u89e3\u8bfb\u3002<\/p>\n<\/section>\n<p>\u8fd9\u5e76\u4e0d\u662f\u8981\u5426\u5b9a\u59dc\u9ec4\u7d20\u7684\u4ef7\u503c\uff0c\u800c\u662f\u8981\u6b63\u89c6\u4e00\u4e2a\u88ab\u957f\u671f\u4f4e\u4f30\u7684\u5929\u7136\u6210\u5206--<strong>\u4e73\u9999\u63d0\u53d6\u7269\uff08Boswellia serrata\uff09<\/strong>\uff0c\u4ee5\u53ca\u5b83\u5982\u4f55\u51ed\u501f\u72ec\u7279\u7684\u7cbe\u51c6\u9776\u70b9\u548c\u5feb\u901f\u8d77\u6548\u80fd\u529b\uff0c\u91cd\u65b0\u5b9a\u4e49\u4e86\u201c\u5929\u7136\u6297\u708e\u201d\u7684\u8fb9\u754c\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section>\n<section>&nbsp;<\/p>\n<p><strong>\u90a3\u6761\u88ab\u5ffd\u89c6\u7684\u81f4\u75db\u901a\u8def<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section>&nbsp;<\/p>\n<p>\u8981\u7406\u89e3\u4e73\u9999\u7684\u4e0d\u53ef\u66ff\u4ee3\u6027\uff0c\u9700\u8981\u56de\u5230\u708e\u75c7\u7684\u751f\u5316\u6e90\u5934\u3002\u5f53\u7ec6\u80de\u819c\u5728\u708e\u75c7\u523a\u6fc0\u4e0b\u91ca\u653e\u82b1\u751f\u56db\u70ef\u9178\u540e\uff0c\u5b83\u4f1a\u6cbf\u4e24\u6761\u4e0e\u5173\u8282\u708e\u75c7\u6700\u4e3a\u76f8\u5173\u7684\u6838\u5fc3\u901a\u8def\u8fdb\u884c\u4ee3\u8c22\uff1a<\/p>\n<section><\/section>\n<ul class=\"list-paddingleft-2\">\n<li><strong>\u4e00\u6761\u7ecf\u7531\u73af\u6c27\u5408\u9176\uff08COX\uff09\u8f6c\u5316\u4e3a\u524d\u5217\u817a\u7d20<\/strong>\uff0c\u5f15\u53d1\u7ea2\u3001\u80bf\u3001\u70ed\u3001\u75db\u7b49\u5178\u578b\u708e\u75c7\u53cd\u5e94\uff0c\u8fd9\u4e5f\u662f\u5e03\u6d1b\u82ac\u7b49\u975e\u753e\u4f53\u6297\u708e\u836f\uff08NSAIDs\uff09\u7684\u4e3b\u8981\u4f5c\u7528\u9776\u70b9\uff1b<\/li>\n<li><strong>\u53e6\u4e00\u6761\u5219\u901a\u8fc75-\u8102\u6c27\u5408\u9176\uff085-LOX\uff09\u751f\u6210\u767d\u4e09\u70ef<\/strong>\u3002\u767d\u4e09\u70ef\u4e0d\u4ec5\u662f\u54ee\u5598\u548c\u8fc7\u654f\u6027\u708e\u75c7\u7684\u5173\u952e\u9a71\u52a8\u56e0\u5b50\uff0c\u5728\u5173\u8282\u6ed1\u6db2\u4e2d\uff0c\u5b83\u540c\u6837\u662f\u5bfc\u81f4\u987d\u56fa\u6027\u80bf\u80c0\u3001\u6668\u50f5\u548c\u5267\u70c8\u75bc\u75db\u7684\u91cd\u8981\u4ecb\u8d28\u3002<\/li>\n<\/ul>\n<section><\/section>\n<section>&nbsp;<\/p>\n<\/section>\n<p>\u59dc\u9ec4\u7d20\u7684\u5e7f\u8c31\u6297\u708e\u673a\u5236\uff0c\u51b3\u5b9a\u4e86\u5b83\u4e3b\u8981\u5728\u4e0a\u6e38\u8c03\u8282NF-\u03baB\u8fd9\u4e00\u201c\u603b\u5f00\u5173\u201d\uff0c\u8fdb\u800c\u6291\u5236COX-2\u3001TNF-\u03b1\u7b49\u4e0b\u6e38\u901a\u8def\uff0c<strong>\u4f46\u5bf95-LOX\u7684\u76f4\u63a5\u6291\u5236\u76f8\u5bf9\u6709\u9650<\/strong>\u3002\u8fd9\u610f\u5473\u7740\uff0c\u5f53\u5173\u8282\u75bc\u75db\u66f4\u591a\u7531\u767d\u4e09\u70ef\u9a71\u52a8\u65f6\uff0c\u5355\u7eaf\u4f9d\u8d56\u59dc\u9ec4\u7d20\u5f88\u96be\u5728\u77ed\u671f\u5185\u83b7\u5f97\u6ee1\u610f\u7684\u7f13\u89e3\u6548\u679c\u3002\u8fd9\u4e5f\u89e3\u91ca\u4e86\u4e3a\u4ec0\u4e48\u6709\u7ecf\u9a8c\u7684\u4e34\u5e8a\u89c2\u5bdf\u4f1a\u53d1\u73b0\uff0c\u90e8\u5206\u9aa8\u5173\u8282\u708e\u60a3\u8005\u7684\u5173\u8282\u79ef\u6db2\u548c\u50f5\u786c\uff0c\u5bf9\u59dc\u9ec4\u7d20\u7684\u53cd\u5e94\u65f6\u95f4\u9700\u89814~12\u5468\u4e4b\u4e45\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section>\n<section>&nbsp;<\/p>\n<p><strong>\u4e73\u9999\u63d0\u53d6\u7269\uff1a<\/strong><strong>\u4e13\u653b5-LOX\uff0c\u6539\u5199\u60c5\u7eea\u8bb0\u5fc6<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section>&nbsp;<\/p>\n<p>\u4e73\u9999\u7684\u836f\u7528\u53f2\u53ef\u4ee5\u8ffd\u6eaf\u5230\u53e4\u57c3\u53ca\u548c\u963f\u80b2\u5420\u9640\u533b\u5b66\uff0c\u4f46\u73b0\u4ee3\u79d1\u5b66\u76f4\u5230\u8fd1\u5e74\u624d\u9501\u5b9a\u5176\u6838\u5fc3\u6b66\u5668\u2014\u2014<strong>\u4e59\u9170-11-\u916e-\u03b2-\u4e73\u9999\u9178\uff08AKBA\uff09<\/strong>\u3002AKBA\u51e0\u4e4e\u4ee5\u4e00\u79cd\u201c\u7cbe\u51c6\u5236\u5bfc\u201d\u7684\u65b9\u5f0f\uff0c<strong>\u9ad8\u6548\u6291\u52365-LOX\u7684\u6d3b\u6027<\/strong>\uff0c\u4ece\u6e90\u5934\u6390\u65ad\u767d\u4e09\u70ef\u7684\u5408\u6210\u3002\u8fd9\u79cd\u4e13\u4e00\u6027\u5e26\u6765\u4e86\u4e24\u4e2a\u76f4\u63a5\u4e14\u5173\u952e\u7684\u4f18\u52bf\uff1a\u4e00\u662f\u4e0d\u6291\u5236COX-1\uff0c\u56e0\u6b64\u4e0d\u635f\u4f24\u80c3\u9ecf\u819c\uff0c\u53cd\u800c\u6709\u4fdd\u62a4\u80c3\u80a0\u7684\u6f5c\u529b\uff1b\u4e8c\u662f\u5b83\u80fd\u5feb\u901f\u524a\u51cf\u7531\u767d\u4e09\u70ef\u4ecb\u5bfc\u7684\u5173\u8282\u80bf\u80c0\u548c\u75bc\u75db\u3002<\/p>\n<section><\/section>\n<section>&nbsp;<\/p>\n<\/section>\n<p>\u7136\u800c\uff0c\u4e73\u9999\u7684\u9547\u75db\u4ef7\u503c\u8fdc\u4e0d\u6b62\u4e8e\u5916\u5468\u6297\u708e\u30022025\u5e74\u7684\u8fd9\u9879\u968f\u673a\u53cc\u76f2\u5b89\u6170\u5242\u5bf9\u7167\u8bd5\u9a8c\uff0c\u9996\u6b21\u5229\u7528\u77ed\u683c\u5f0f\u9ea6\u5409\u5c14\u75bc\u75db\u95ee\u5377\uff08SF-MPQ\uff09\u7cfb\u7edf\u89e3\u6784\u4e86\u75bc\u75db\u7684\u53cc\u91cd\u7ef4\u5ea6\u2014\u2014\u611f\u89c9\u6027\u75bc\u75db\uff08\u5982\u523a\u75db\u3001\u9178\u75db\u3001\u640f\u52a8\u6027\u75bc\u75db\uff09\u548c\u60c5\u611f\u6027\u75bc\u75db\uff08\u5982\u75b2\u60eb\u8017\u7aed\u611f\u3001\u6050\u60e7\u3001\u6298\u78e8\u611f\uff09[1]\u3002<\/p>\n<section><\/section>\n<section>&nbsp;<\/p>\n<\/section>\n<section>\n<section>\n<section>\u7814\u7a76\u7ed3\u679c\u63d0\u4f9b\u4e86\u82e5\u5e72\u5173\u952e\u6570\u636e\uff1a\u6cbb\u7597\u7ec4\u57286\u5c0f\u65f6\u5185\u75bc\u75db\u6574\u4f53\u51cf\u8f7b98%\uff0c\u89c6\u89c9\u6a21\u62df\u8bc4\u5206\uff08VAS\uff09\u4e0b\u964d97.38%\uff0c\u5f53\u524d\u75bc\u75db\u5f3a\u5ea6\uff08PPI\uff09\u6539\u558496.01%\u3002\u5728\u5206\u7ef4\u5ea6\u6307\u6807\u4e0a\uff0c\u53d8\u5316\u540c\u6837\u663e\u8457\u2014\u2014\u60c5\u611f\u6027\u63cf\u8ff0\u8bcd\u201c\u75b2\u52b3-\u8017\u5c3d\u611f\u201d\u7684\u62a5\u544a\u6bd4\u4f8b\u4ece\u6cbb\u7597\u524d\u768461%\u4e0b\u964d\u81f33%\uff0c\u611f\u89c9\u6027\u63cf\u8ff0\u8bcd\u201c\u538b\u75db\u201d\u4ece65%\u4e0b\u964d\u81f31%\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<p>\u8fd9\u4e9b\u6570\u636e\u63d0\u793a\uff0c\u75bc\u75db\u7684\u60c5\u611f\u7ef4\u5ea6\u4e0e\u5927\u8111\u8fb9\u7f18\u7cfb\u7edf\u7684\u5904\u7406\u5bc6\u5207\u76f8\u5173\uff0c\u5176\u8bc4\u5206\u7684\u5feb\u901f\u4e0b\u964d\u6697\u793a\u8be5\u914d\u65b9\u53ef\u80fd\u5bf9\u4e2d\u67a2\u75d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class=\"group-empty\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section><\/section>\n<section>\n<section>\n<section>\n<section><strong>\u53c2\u8003\u6587\u732e\/\u8d44\u6599<\/strong><\/p>\n<\/section>\n<section>[1] Modulation of Affective and Sensory Qualities of Acute Nociceptive Pain by Curcuma longa and Boswellia serrata Extract Formulation: A Randomized, Double-Blind, Placebo-Controlled Design in Subjects With Exercise-Induced Acute Musculoskeletal Pain. 2025.<\/p>\n<p>[2] Evaluating the efficacy and safety of Curcuma longa, Boswellia serrata, and their mixed formulation in treating knee osteoarthritis: A systematic review and network meta-analysis. 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