{"id":6229,"date":"2026-06-07T09:51:39","date_gmt":"2026-06-07T01:51:39","guid":{"rendered":"https:\/\/www.tinusgroup.com\/ingredients\/cinmn\/"},"modified":"2026-06-09T11:38:16","modified_gmt":"2026-06-09T03:38:16","slug":"cinmn","status":"publish","type":"ingredients","link":"https:\/\/www.tinusgroup.com\/en\/ingredients\/cinmn\/","title":{"rendered":"ciNMN\u00ae"},"content":{"rendered":"<p>A revolutionary compound NMN ingredient that solves the problem of NAM accumulation caused by single NMN by inhibiting CD38\/CD157 activity and activating NAMPT.<\/p>\n<h3>Formula Advantages<\/h3>\n<ul>\n<li>Dual pathways break through the NMN bottleneck: while supplementing NMN, inhibiting CD38\/CD157 to reduce non-productive consumption of NAD+, and activating NAMPT to recycle nicotinamide, forming an efficient closed loop of NAD+ synthesis and regeneration.<\/li>\n<li>Targeted inhibition of CD38\/CD157: The core active component Q45-Q70 has been verified by molecular simulations and experiments to effectively inhibit the activity of aging-related CD38\/CD157 enzymes and prevent them from degrading NMN and its precursors.<\/li>\n<li>Activate NAMPT to clear NAM: Promote nicotinamide recycling through natural NAMPT activators, significantly reduce NAM accumulation and avoid potential adverse reactions<\/li>\n<li>Enhance overall anti-aging efficacy: Ensure NMN is more effective in increasing NAD+ levels, supporting the longevity protein Sirtuin family and DNA repair enzyme functions<\/li>\n<\/ul>\n","protected":false},"featured_media":0,"template":"","ingredient_category":[],"class_list":["post-6229","ingredients","type-ingredients","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.tinusgroup.com\/en\/wp-json\/wp\/v2\/ingredients\/6229","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tinusgroup.com\/en\/wp-json\/wp\/v2\/ingredients"}],"about":[{"href":"https:\/\/www.tinusgroup.com\/en\/wp-json\/wp\/v2\/types\/ingredients"}],"wp:attachment":[{"href":"https:\/\/www.tinusgroup.com\/en\/wp-json\/wp\/v2\/media?parent=6229"}],"wp:term":[{"taxonomy":"ingredient_category","embeddable":true,"href":"https:\/\/www.tinusgroup.com\/en\/wp-json\/wp\/v2\/ingredient_category?post=6229"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}